Rafael Nunez Airport to Barajas Airport / Flights from US$427 incl. tax

Based on HopeGoo data, Plus Ultra Lineas Aereas offers one-way fares as low as US$420 on Cheapest nonstop routes (e.g. CTG to MAD on Wed, Apr 22), while avianca offers Cheapest nonstop round-trips from US$729 departing on Wed, Apr 15 and returning on Wed, Apr 22.

At the moment, you can catch a nonstop flight from Cartagena to Madrid with the following airlines, including: Plus Ultra Lineas Aereas World2Fly Selected airlines are based on historical data collected from flight bookings users made on HopeGoo within the last 90 days.

It takes about 10 hours 1 minute to fly from Cartagena to Madrid.

By analyzing data from all airlines on the HopeGoo flight calendar, it looks like the best time to book a flight from Cartagena to Madrid is around 40 days (6 weeks) in advance, and the best time to fly is usually on Tuesday, Wednesday, and Saturday. Tuesday typically offers the cheapest flights for departure, while Saturday offers the best return deals.

Based on HopeGoo data in the past 4 weeks, there is 4 flight per week flying from Cartagena to Madrid. You can check the weekly schedule for popular airlines on this route below: Plus Ultra Lineas Aereas: -/-/-/-/-/-/- -- PU231 (03:24) Plus Ultra Lineas Aereas: S/-/T/-/-/F/- -- PU221 (00:41)

To find best deals on flights from Cartagena to Madrid, you can use various tools on HopeGoo: · Be flexible with your travel dates to get the cheapest flight deal. Now the cheapest flight deal is on Wed, Apr 22, with one-way flights priced at just US$420. · Compare airlines strategically. Budget carriers often provide the lowest base fares, while we found the most affordable airline currently operating on this route is Plus Ultra Lineas Aereas. · Set up price alerts to easily monitor ticket prices without having to check every day. · Check HopeGoo flight deals and promo codes frequently. · Avoid peak season unless you book very early. It seems the peak season for Madrid travel is around January. · Get exclusive promo codes for HopeGoo app users.

The cheapest months to fly from Cartagena to Madrid is September, when demand for travel is lower.

After crunching the numbers on our March flight calendar, it's currently cheapest to fly from Cartagena to Madrid on March 4, 2026 with Plus Ultra Lineas Aereas, with prices starting at US$469.

You can land at any one of the following hubs in Madrid, with Rafael Nunez International Airport to Madrid Barajas Airport (CTG-MAD) is by far the most common option on this route: Madrid Barajas Airport (MAD).

The time difference between Madrid and Cartagena is 6h.

Tickets can only be changed or canceled if permitted by airline policy. To submit a change or cancellation request, go to the flight bookings page, select the option to change or cancel your HopeGoo, choose the relevant passengers and segment, and submit a request. Please note that additional charges may apply according to the airline ticket policy. However, if the flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For more details about change and cancellation policies, please check the customer support pages.