Cusco to Antofagasta Flights

Based on HopeGoo data, LATAM Airlines offers one-way fares as low as US$135 on Cheapest nonstop routes (e.g. CUZ to ANF on Wed, Apr 8), while LATAM Airlines offers Cheapest nonstop round-trips from US$343 departing on Sun, Mar 29 and returning on Sun, Apr 5.

By analyzing data from all airlines on the HopeGoo flight calendar, it looks like the best time to book a flight from Cusco to Antofagasta is around 40 days (6 weeks) in advance, and the best time to fly is usually on Tuesday, Wednesday, and Saturday. Tuesday typically offers the cheapest flights for departure, while Saturday offers the best return deals.

To find best deals on flights from Cusco to Antofagasta, you can use various tools on HopeGoo: · Be flexible with your travel dates to get the cheapest flight deal. Now the cheapest flight deal is on Wed, Apr 8, with one-way flights priced at just US$135. · Compare airlines strategically. Budget carriers often provide the lowest base fares, while we found the most affordable airline currently operating on this route is LATAM Airlines. · Set up price alerts to easily monitor ticket prices without having to check every day. · Check HopeGoo flight deals and promo codes frequently. · Avoid peak season unless you book very early. It seems the peak season for Antofagasta travel is around August. · Get exclusive promo codes for HopeGoo app users.

The cheapest months to fly from Cusco to Antofagasta is October, when demand for travel is lower.

After crunching the numbers on our March flight calendar, it's currently cheapest to fly from Cusco to Antofagasta on March 29, 2026 with LATAM Airlines, with prices starting at US$343.

The time difference between Antofagasta and Cusco is 1h.

Tickets can only be changed or canceled if permitted by airline policy. To submit a change or cancellation request, go to the flight bookings page, select the option to change or cancel your HopeGoo, choose the relevant passengers and segment, and submit a request. Please note that additional charges may apply according to the airline ticket policy. However, if the flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For more details about change and cancellation policies, please check the customer support pages.