Guadalajara to Santiago Flights

Based on HopeGoo data, LATAM Airlines offers one-way fares as low as US$648 on Cheapest nonstop routes (e.g. GDL to SCL on Thu, Mar 19), while Copa Airlines offers Cheapest nonstop round-trips from US$732 departing on Sun, Apr 5 and returning on Fri, Apr 10.

By analyzing data from all airlines on the HopeGoo flight calendar, it looks like the best time to book a flight from Guadalajara to Santiago is around 40 days (6 weeks) in advance, and the best time to fly is usually on Tuesday, Wednesday, and Saturday. Tuesday typically offers the cheapest flights for departure, while Saturday offers the best return deals.

To find best deals on flights from Guadalajara to Santiago, you can use various tools on HopeGoo: · Be flexible with your travel dates to get the cheapest flight deal. Now the cheapest flight deal is on Thu, Mar 19, with one-way flights priced at just US$648. · Compare airlines strategically. Budget carriers often provide the lowest base fares, while we found the most affordable airline currently operating on this route is LATAM Airlines. · Set up price alerts to easily monitor ticket prices without having to check every day. · Check HopeGoo flight deals and promo codes frequently. · Avoid peak season unless you book very early. It seems the peak season for Santiago travel is around July. · Get exclusive promo codes for HopeGoo app users.

The cheapest months to fly from Guadalajara to Santiago is October, when demand for travel is lower.

After crunching the numbers on our March flight calendar, it's currently cheapest to fly from Guadalajara to Santiago on March 17, 2026 with Aeromexico, with prices starting at US$596.

The time difference between Santiago and Guadalajara is 2h.

Tickets can only be changed or canceled if permitted by airline policy. To submit a change or cancellation request, go to the flight bookings page, select the option to change or cancel your HopeGoo, choose the relevant passengers and segment, and submit a request. Please note that additional charges may apply according to the airline ticket policy. However, if the flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For more details about change and cancellation policies, please check the customer support pages.