PSA to BRU, Pisa International Airport to Brussels Airport Cheap Flights

Based on HopeGoo data, Ryanair offers one-way fares as low as US$23 on Cheapest nonstop routes (e.g. PSA to CRL on Wed, Apr 29), while Ryanair offers Cheapest nonstop round-trips from US$58 departing on Wed, Mar 18 and returning on Sat, Mar 21.

At the moment, you can catch a nonstop flight from Pisa to Brussels with the following airlines, including: Ryanair Selected airlines are based on historical data collected from flight bookings users made on HopeGoo within the last 90 days.

It takes about 1 hour 40 minutes to fly from Pisa to Brussels.

By analyzing data from all airlines on the HopeGoo flight calendar, it looks like the best time to book a flight from Pisa to Brussels is around 40 days (6 weeks) in advance, and the best time to fly is usually on Tuesday, Wednesday, and Saturday. Tuesday typically offers the cheapest flights for departure, while Saturday offers the best return deals.

Based on HopeGoo data in the past 4 weeks, there is 10 flight per week flying from Pisa to Brussels. You can check the weekly schedule for popular airlines on this route below: Ryanair: S/-/-/W/-/F/- -- FR3747 (08:46) Ryanair: S/M/T/W/T/F/S -- FR3746 (15:43)

To find best deals on flights from Pisa to Brussels, you can use various tools on HopeGoo: · Be flexible with your travel dates to get the cheapest flight deal. Now the cheapest flight deal is on Wed, Apr 29, with one-way flights priced at just US$23. · Compare airlines strategically. Budget carriers often provide the lowest base fares, while we found the most affordable airline currently operating on this route is Ryanair. · Set up price alerts to easily monitor ticket prices without having to check every day. · Check HopeGoo flight deals and promo codes frequently. · Avoid peak season unless you book very early. It seems the peak season for Brussels travel is around January. · Get exclusive promo codes for HopeGoo app users.

The cheapest months to fly from Pisa to Brussels is October, when demand for travel is lower.

After crunching the numbers on our February flight calendar, it's currently cheapest to fly from Pisa to Brussels on February 28, 2026 with Ryanair, with prices starting at US$49.

You can land at any one of the following hubs in Brussels, with Pisa International Airport to Brussels South Charleroi Airport (PSA-CRL) is by far the most common option on this route: Brussels Airport (BRU) Brussels South Charleroi Airport (CRL).

The time difference between Brussels and Pisa is 0h.

Tickets can only be changed or canceled if permitted by airline policy. To submit a change or cancellation request, go to the flight bookings page, select the option to change or cancel your HopeGoo, choose the relevant passengers and segment, and submit a request. Please note that additional charges may apply according to the airline ticket policy. However, if the flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For more details about change and cancellation policies, please check the customer support pages.