PTY to MAD, Tocumen International Airport to Madrid Barajas Airport Cheap Flights

Based on HopeGoo data, Copa Airlines offers one-way fares as low as US$499 on Cheapest nonstop routes (e.g. PTY to MAD on Thu, Feb 12), while Air Europa offers Cheapest nonstop round-trips from US$640 departing on Tue, Mar 10 and returning on Thu, Mar 12.

At the moment, you can catch a nonstop flight from Panama City to Madrid with the following airlines, including: Air Europa Iberia Selected airlines are based on historical data collected from flight bookings users made on HopeGoo within the last 90 days.

It takes about 9 hours 50 minutes to fly from Panama City to Madrid.

By analyzing data from all airlines on the HopeGoo flight calendar, it looks like the best time to book a flight from Panama City to Madrid is around 40 days (6 weeks) in advance, and the best time to fly is usually on Tuesday, Wednesday, and Saturday. Tuesday typically offers the cheapest flights for departure, while Saturday offers the best return deals.

Based on HopeGoo data in the past 4 weeks, there is 14 flight per week flying from Panama City to Madrid. You can check the weekly schedule for popular airlines on this route below: Air Europa: S/M/T/W/T/F/S -- UX056 (22:30)

To find best deals on flights from Panama City to Madrid, you can use various tools on HopeGoo: · Be flexible with your travel dates to get the cheapest flight deal. Now the cheapest flight deal is on Thu, Feb 12, with one-way flights priced at just US$499. · Compare airlines strategically. Budget carriers often provide the lowest base fares, while we found the most affordable airline currently operating on this route is Air Europa. · Set up price alerts to easily monitor ticket prices without having to check every day. · Check HopeGoo flight deals and promo codes frequently. · Avoid peak season unless you book very early. It seems the peak season for Madrid travel is around January. · Get exclusive promo codes for HopeGoo app users.

The cheapest months to fly from Panama City to Madrid is August, when demand for travel is lower.

After crunching the numbers on our February flight calendar, it's currently cheapest to fly from Panama City to Madrid on February 17, 2026 with Copa Airlines, with prices starting at US$514.

You can land at any one of the following hubs in Madrid, with Tocumen International Airport to Madrid Barajas Airport (PTY-MAD) is by far the most common option on this route: Madrid Barajas Airport (MAD).

The time difference between Madrid and Panama City is 6h.

Tickets can only be changed or canceled if permitted by airline policy. To submit a change or cancellation request, go to the flight bookings page, select the option to change or cancel your HopeGoo, choose the relevant passengers and segment, and submit a request. Please note that additional charges may apply according to the airline ticket policy. However, if the flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For more details about change and cancellation policies, please check the customer support pages.