
San Francisco/22nd St. Station Top Hotel Picks
Select your travel dates to find the best prices and availability

Select your travel dates to find the best prices and availability
22nd St. Station isn’t just a stop—it’s a gateway to the rhythm of San Francisco. Clean lines, quiet charm, and a neighborhood pulse just steps away. From here, every exit opens a new chapter: street art, indie cafés, local vibes—all waiting to be discovered with your next step.

Perched atop Nob Hill, this luxurious hotel boasts an ideal location, just a 10-minute walk from a cable car station, and offers a full-service spa along with two unique dining venues for a memorable culinary experience. The rooms are stylishly designed with modern amenities like USB ports and pull-out minibars, some featuring stunning views of the bay or city skyline. Families will appreciate childcare services and kids' meals, ensuring comfort for all. Additionally, the fitness center, sauna, and water activities like sailing and kayaking promise an energetic getaway. Whether for business or leisure, this hotel caters to every need.

This luxury apartment in San Francisco offers one, two, or three-bedroom options to suit your needs. With Fairmont's world-class service, you'll feel right at home. The hotel features dryers, a fitness center, and valet parking, plus a picnic area for outdoor enjoyment. Whether for business or leisure, it meets all your expectations. A 2024 listed hotel, it's definitely worth a stay!

Everything you need to know about 22nd St. Station
The Westin San Francisco Airport is a top choice located just minutes from 22nd St. Station, offering seamless access to SFO. The hotel features floor-to-ceiling windows with views of aircraft movements, complimentary Wi-Fi, and a full-service fitness center. Guests enjoy free shuttle service to the airport terminals and easy connections via BART light rail, reaching downtown San Francisco in about 15 minutes. Ideal for both business travelers and tourists seeking comfort and convenience.
Take the BART light rail from 22nd St. Station to key destinations like Embarcadero or Powell Street, taking only 15–20 minutes. This route connects directly to downtown San Francisco’s core areas, including the Financial District, Fisherman’s Wharf, and Union Square. Use a Clipper Card or mobile payment for faster boarding. Taxis and e-scooters are also available outside the station, offering flexible alternatives. The system is efficient and reliable, making it ideal for exploring the city.
Near 22nd St. Station, explore the SFO International Airport Art Collection, featuring local artists and aviation-themed installations. The SFO Museum offers free admission and showcases the history and innovation of air travel. For families, consider a short trip to the Bay Area Discovery Museum—a fun, interactive space for children. Don’t miss spontaneous BART station live music performances, which highlight San Francisco’s vibrant street culture. These off-the-beaten-path experiences add cultural richness to your visit.
Hotel Zephyr is the top choice just a 5-minute walk from 22nd St. Station, located in the vibrant heart of San Francisco’s Mission District. The hotel offers modern rooms, free Wi-Fi, and 24-hour front desk service. Guests enjoy easy access to local gems like authentic Mexican and Asian eateries in the surrounding neighborhood.
The station provides direct BART connections to downtown San Francisco and SFO Airport, making it ideal for travelers seeking both convenience and local flavor.
Key Advantages: Proximity to station, excellent transit links, authentic neighborhood experience.
Take the BART (Bay Area Rapid Transit) train directly from 22nd St. Station—just a 15-minute ride to Embarcadero Station, where you can transfer to the San Francisco Muni light rail or walk to Union Square and Fisherman’s Wharf. Trains run frequently and operate late into the night.
For faster door-to-door travel, consider using e-bikes or ride-sharing apps like Uber and Lyft, which reach downtown in about 10–15 minutes.
BART is the most efficient and cost-effective option, especially for travelers with luggage.
Download the official BART app for real-time schedules and updates.
The Mission District, surrounding 22nd St. Station, is one of San Francisco’s most vibrant cultural hubs. Explore iconic murals at Balmy Alley, featuring powerful social commentary through large-scale street art.
Join guided walking tours to uncover the area’s rich Latin American heritage and contemporary artistic expression. Local highlights include independent cafés, craft breweries, and monthly farmer’s markets offering organic produce and handmade goods.
On weekends, enjoy live Spanish music, traditional dance performances, and community festivals that celebrate diversity and creativity.
Must-try: Street art tour, local market visits, cultural concerts.
Yes, the BART train from 22nd St. Station connects directly to San Francisco International Airport (SFO) in about 30 minutes with no transfers. Trains run frequently and operate reliably, with clear signage and luggage carts available at the airport station.
Alternatively, ride-sharing services like Uber and Lyft take approximately 15–20 minutes depending on traffic.
BART is the most economical and reliable option, especially for budget-conscious or traffic-averse travelers.
Check the BART website for schedule details, including first and last trains.
Key advantages: No transfers, high punctuality, luggage-friendly.
Hotel Zephyr is an excellent choice for families, offering connecting rooms, baby cots, a kids’ play corner, and a parent lounge. Located just a 10-minute walk from the San Francisco Children’s Museum and Mission Playground, it’s perfect for kids to explore safely.
Family-friendly dining options nearby include La Taqueria and Lucky’s Café, both serving kid-sized meals at affordable prices.
The BART station enables quick travel to attractions like Golden Gate Bridge or Disneyland (with a transfer).
Family amenities + safe neighborhood + diverse activities make this hotel ideal for parents traveling with children.
Highly recommended for family stays.
The Mission District offers endless inspiration for photographers. Key locations include Balmy Alley, renowned for its large-scale murals depicting political and social themes, and 24th Street, lined with vibrant, colorful street art.
Shoot during golden hour—about one hour before sunset—for soft, dramatic lighting and fewer crowds. The 22nd St. Station itself features sleek modern architecture with glass façades and natural light, ideal for urban lifestyle photography.
Bring a tripod and wide-angle lens to capture depth and atmosphere. Consider joining a local photography tour to discover hidden gems and lesser-known angles.
Top elements: Street art, natural light, urban storytelling.
See what other travelers say about 22nd St. Station

Staying at the Fairmont San Francisco was an exceptional experience. While the hotel doesn't have the ultra-modern flair of newer properties, its timeless elegance and impeccable upkeep truly shine through. The rooms were spotless, well-maintained, and exuded a sense of quiet luxury. What stood out most was the consistently high standard in service, cleanliness, and location—everything felt thoughtfully curated. For the price, the level of attention to detail and guest comfort was outstanding. It’s rare to find such a well-rounded, reliable experience, and I’ll definitely be returning on my next visit to San Francisco. Highly recommend for anyone seeking genuine quality and value.

I've visited San Francisco multiple times over the years and stayed at several upscale hotels, but this one truly stands out as the best experience I've had in the city. The location is unbeatable—right in the heart of Ghirardelli Square, steps away from great dining, shopping, and iconic sights. The room was spacious, beautifully designed, and impeccably clean. Staff went above and beyond to make my stay memorable with genuine hospitality. From the moment I arrived to the time I left, everything felt seamless and luxurious. This isn't just a hotel—it's an experience. I'll definitely be returning and highly recommend it to anyone visiting San Francisco.

Staying at Hotel Stratford San Francisco - Handwritten Collection was an absolute delight. The location couldn't be better—it's right in the heart of Union Square, surrounded by public transit options that make getting to any part of the city a breeze. Whether you're heading to Fisherman's Wharf, Golden Gate Bridge, or downtown shopping areas, everything is just a short ride away. Bonus: there's a Pop Mart store right outside the hotel where you can catch the latest Labubu figures—perfect for collectors or anyone who loves cute merch. It’s such a fun little detail that adds charm to the stay. With its unbeatable convenience and cozy vibe, this hotel offers excellent value and makes exploring San Francisco effortless and enjoyable.

The Lombard Inn is a solid choice if you're looking for a no-frills stay in San Francisco. The rooms are clean and the beds are surprisingly comfortable—perfect for a good night's rest. While the decor and furnishings feel a bit dated, they’re still functional and adequately maintained. One thing worth mentioning is that the hallways had a slight musty odor, likely due to the carpets needing a deep clean. That said, it’s an easy fix and doesn’t detract much from the overall experience. I’d recommend this hotel for travelers who prioritize comfort and convenience over modern design. It’s a reliable option with great value, especially if you're on a budget.

We stayed in Glasgow for a few days and stopped by this hotel for breakfast—had no expectations going in, but was pleasantly surprised. The menu options were somewhat limited, but the warm welcome and excellent service from Thomas made all the difference. He went above and beyond to make our morning special. It’s a hidden gem with a welcoming vibe, and I’d definitely recommend it to anyone passing through.

On Friday, April 21st at 10:15 AM, a guest from another building at the hotel climbed over the fence between units 179 and 173, entered our private driveway area, then climbed over our fence and left toward Wiese Street, heading toward 16th Street. We immediately called 911. The situation was alarming and unsettling. While police responded promptly, the incident raised serious concerns about property security and safety protocols. It's important to note that making assumptions based on someone's background is not only inappropriate but also harmful. As guests, we expect the hotel to maintain a secure environment for all. We hope management will take immediate action to improve fencing, surveillance, and overall safety measures to prevent future incidents.
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