Hotel Santa Caterina is a top choice, just a 3-minute walk from Antica Drogheria Manganelli 1879. This boutique hotel features private balconies overlooking ancient rooftops and offers a complimentary Tuscan-style breakfast with local spices and olive oil. Guests receive a curated gift box of heritage ingredients, enhancing your sensory journey through Siena’s culinary roots.

Palazzo Della Pergola boasts panoramic terrace rooms facing the historic square, offering direct views of Antica Drogheria Manganelli 1879's vintage façade. The hotel provides personalized guided walks through hidden alleyways and hosts exclusive wine tastings featuring regional recipes enhanced by century-old spice blends, immersing guests in 19th-century Tuscan trade culture.

Stay at Casa del Canto, a heritage villa turned boutique guesthouse, where daily handcrafted spice workshops use authentic ingredients sourced directly from Antica Drogheria Manganelli 1879. Guests learn to prepare traditional Italian seasonings with dried fruits and herbs. The hotel also offers an evening historic lighting tour, wandering through stone alleys illuminated by vintage lanterns, capturing the soulful quiet of Siena’s ancient streets.