| 1 | Hilton Wuhan Optics Valley | ★★★★★ | 4.8 | 4598 | 6.69 km | No. 9 Chunhe Road |
| 2 | Crowne Plaza Wuhan Optics Valley Hotel | ★★★★★ | 4.9 | 4701 | 5.16 km | No.668 Gaoxin Avenue |
| 3 | Wyndham Garden Wuhan Optics Valley Hotel | ★★★★★ | 4.9 | 4446 | 4.17 km | Building 2, No.58 Guanggu Fourth Road, Donghu New Technology Development Zone, Wuhan City |
| 4 | Wuhan Marriott Hotel Optics Valley | ★★★★★ | 4.8 | 1643 | 2.05 km | No. 797 Gaoxin Avenue |
| 5 | Moon Hotel | ★★★★ | 4.9 | 2378 | 6.76 km | No. 9 Huacheng Avenue (Wuhan Software New City) |
| 6 | QUEENS VILLA | ★★★★ | 4.9 | 1705 | 5.3 km | Room Department of Erfei Villa, Optics Valley Bio-City, No. 666 Gaoxin Avenue, Donghu New Technology Development Zone, Wuhan |
| 7 | Wingate by Wyndham Wuhan Optics Valley | ★★★★ | 4.9 | 2721 | 2.15 km | No.792 Gaoxin Avenue |
| 8 | Wuhan Optics Valley Technology Exhibition Center Exhibition Hotel | ★★★★ | 4.8 | 820 | 2.35 km | No.787 Gaoxin Avenue |
| 9 | Wuhan Howard Johnson Optics Valley Hotel | ★★★★ | 4.9 | 671 | 1.61 km | No.801 Gaoxin Avenue, Wuhan East Lake High-Tech Development Zone |
| 10 | Radisson Red Wuhan Optics Valley Science & Technology Exhibition Center Grand Joy City | ★★★★ | 4.9 | 2864 | 2.77 km | BuildingA1, Huaxiang Center, No. 776 Gaoxin Avenue |
| 11 | Vienna International Hotel | ★★★★ | 4.7 | 948 | 6.92 km | Hubei Natural Gas Building, 618 Guanggu Third Road, Hubei Province, China |
| 12 | IntercityHotel | ★★★★ | 4.9 | 1685 | 3.28 km | Building One, CADE Center, No. 28, Optics Valley Fifth Road, Wuhan. China |
| 13 | Jianguo Hidden Hotel (Wuhan Optics Valley Science and Technology Convention Center Joy City Branch) | ★★★★ | 4.8 | 427 | 2.23 km | China Hubei Wuhan Hongshan District East Lake New Technology Development Zone Guanggu Six Road Changjiang Digital Culture Industry Park Building A2 |
| 14 | Hampton by Hilton Wuhan OVCEC | ★★★★ | 4.9 | 2431 | 1.45 km | No. 50 Gaokeyuan 2nd Road, East Lake High-Tech Development Zone, Wuhan, Hubei Province, China |
| 15 | Wuhan Guanggu Science and Technology Exhibition Centre Qushui Lanting Resort Hotel | ★★★★ | 4.7 | 21 | 4.27 km | 光谷四路70号曲水憩园2号楼 |
| 16 | Home2 Suites by Hilton Wuhan Optics Valley | ★★★★ | 4.9 | 707 | 2.31 km | No.18, Optics Valley Avenue 6th Road, Hongshan District, Wuhan, Hubei, China |
| 17 | The Amber House Wuhan Optics Valley | ★★★★ | 4.9 | 163 | 0.65 km | Building 9, Zhiyu Future, No.17 Optics Valley 7th Road, East Lake High Technology Industrial Development |
| 18 | Golf Hotel Wuhan Yishan | ★★★★ | 4.9 | 23 | 1.95 km | 789 Gaoxin Avenue (Gaoxin Dadao) |
| 19 | JIANGUO PALACE HOTEL | ★★★★ | 4.9 | 563 | 5.18 km | No.668 Gaoxin Avenue East Lake High-tech Development Zone, Wuhan, Hubei Province |
| 20 | Yu Hotel | ★★★★ | 4.9 | 208 | 4.28 km | 光谷四路72号 |