| 1 | Crowne Plaza Wuhan Optics Valley Hotel | ★★★★★ | 4.9 | 4701 | 6.48 km | No.668 Gaoxin Avenue |
| 2 | Wyndham Garden Wuhan Optics Valley Hotel | ★★★★★ | 4.9 | 4446 | 7.08 km | Building 2, No.58 Guanggu Fourth Road, Donghu New Technology Development Zone, Wuhan City |
| 3 | Royal Grace Hotel Optice Valley Wuhan | ★★★★★ | 4.9 | 996 | 4.07 km | No. 2 Daxueyuan Road |
| 4 | Wuhan Marriott Hotel Optics Valley | ★★★★★ | 4.8 | 1643 | 9.12 km | No. 797 Gaoxin Avenue |
| 5 | Four Points by Sheraton Wuhan Optics Valley | ★★★★★ | 4.8 | 153 | 0.57 km | No. 12, Gaoxin 6th Road, Canglong Island, Jiangxia District, Wuhan, Hubei Province |
| 6 | Harvest International Hotel | ★★★★ | 4.8 | 1398 | 5.77 km | 308 Minzu Avenue (Minzu Dadao) |
| 7 | Mercure Hotel | ★★★★ | 4.9 | 1716 | 5.79 km | Building 5, APP Square, No.8 Xiongzhuang Road |
| 8 | Hilton Garden Inn Wuhan Optics Valley | ★★★★ | 4.8 | 475 | 7.11 km | NO.22, 39F, Block 5, Wujiao Xi’an, No. 229, Gaoxin Avenue, East Lake High-tech Development Zone, Wuhan |
| 9 | QUEENS VILLA | ★★★★ | 4.9 | 1705 | 6.23 km | Room Department of Erfei Villa, Optics Valley Bio-City, No. 666 Gaoxin Avenue, Donghu New Technology Development Zone, Wuhan |
| 10 | Wingate by Wyndham Wuhan Optics Valley | ★★★★ | 4.9 | 2721 | 9.06 km | No.792 Gaoxin Avenue |
| 11 | Wuhan Optics Valley Technology Exhibition Center Exhibition Hotel | ★★★★ | 4.8 | 820 | 8.87 km | No.787 Gaoxin Avenue |
| 12 | Palace Hotel (Wuhan Guanggu Financial Port Engineering University) | ★★★★ | 4.9 | 2096 | 2.59 km | South Gate of Wuhan Institute of Technology, 12 Liufang Avenue (Liufang Dadao) |
| 13 | Wuhan Howard Johnson Optics Valley Hotel | ★★★★ | 4.9 | 671 | 9.62 km | No.801 Gaoxin Avenue, Wuhan East Lake High-Tech Development Zone |
| 14 | Radisson Red Wuhan Optics Valley Science & Technology Exhibition Center Grand Joy City | ★★★★ | 4.9 | 2864 | 8.42 km | BuildingA1, Huaxiang Center, No. 776 Gaoxin Avenue |
| 15 | MY·HOTEL | ★★★★ | 4.9 | 2277 | 5.56 km | Block C, Optics Valley Creative Building, 465 Guanshan Avenue, Hongshan District |
| 16 | Metropolo Jinjiang Hotels | ★★★★ | 4.6 | 2338 | 6.66 km | No.39 Guanggu ONE, intersection of Guanggu Avenue and Chuxiong Avenue |
| 17 | Zhongqing TRUE GO Hotel (Wuhan Guanshan Avenue Optics Valley Software Park) | ★★★★ | 4.9 | 3367 | 5.57 km | Block C, Optics Valley Creative Building, 465 Guanshan Avenue |
| 18 | Youth TRUE GO S Hotel (Wuhan University of Media and Communications School of Economics Branch) | ★★★★ | 4.9 | 1229 | 0.88 km | No. 8, Lingjie Roa |
| 19 | The Jade Boutique Hotel | ★★★★ | 4.8 | 516 | 5.51 km | No.7 Guangguruanjianyuan Middle Road |
| 20 | Xin A Dan Yuan Optics Valley International Hotel | ★★★★ | 4.6 | 245 | 2.84 km | No. 112-188 Guanggu Avenue |