| 1 | Crowne Plaza Wuhan Optics Valley Hotel | ★★★★★ | 4.9 | 4701 | 4.78 km | No.668 Gaoxin Avenue |
| 2 | Wyndham Garden Wuhan Optics Valley Hotel | ★★★★★ | 4.9 | 4446 | 3.81 km | Building 2, No.58 Guanggu Fourth Road, Donghu New Technology Development Zone, Wuhan City |
| 3 | Moon Hotel | ★★★★ | 4.9 | 2378 | 6.67 km | No. 9 Huacheng Avenue (Wuhan Software New City) |
| 4 | QUEENS VILLA | ★★★★ | 4.9 | 1705 | 4.93 km | Room Department of Erfei Villa, Optics Valley Bio-City, No. 666 Gaoxin Avenue, Donghu New Technology Development Zone, Wuhan |
| 5 | Wingate by Wyndham Wuhan Optics Valley | ★★★★ | 4.9 | 2721 | 1.86 km | No.792 Gaoxin Avenue |
| 6 | Wuhan Howard Johnson Optics Valley Hotel | ★★★★ | 4.9 | 671 | 1.36 km | No.801 Gaoxin Avenue, Wuhan East Lake High-Tech Development Zone |
| 7 | Radisson Red Wuhan Optics Valley Science & Technology Exhibition Center Grand Joy City | ★★★★ | 4.9 | 2864 | 2.43 km | BuildingA1, Huaxiang Center, No. 776 Gaoxin Avenue |
| 8 | IntercityHotel | ★★★★ | 4.9 | 1685 | 2.93 km | Building One, CADE Center, No. 28, Optics Valley Fifth Road, Wuhan. China |
| 9 | Hampton by Hilton Wuhan OVCEC | ★★★★ | 4.9 | 2431 | 1.34 km | No. 50 Gaokeyuan 2nd Road, East Lake High-Tech Development Zone, Wuhan, Hubei Province, China |
| 10 | Home2 Suites by Hilton Wuhan Optics Valley | ★★★★ | 4.9 | 707 | 2 km | No.18, Optics Valley Avenue 6th Road, Hongshan District, Wuhan, Hubei, China |
| 11 | The Amber House Wuhan Optics Valley | ★★★★ | 4.9 | 163 | 0.86 km | Building 9, Zhiyu Future, No.17 Optics Valley 7th Road, East Lake High Technology Industrial Development |
| 12 | Golf Hotel Wuhan Yishan | ★★★★ | 4.9 | 23 | 1.57 km | 789 Gaoxin Avenue (Gaoxin Dadao) |
| 13 | JIANGUO PALACE HOTEL | ★★★★ | 4.9 | 563 | 4.8 km | No.668 Gaoxin Avenue East Lake High-tech Development Zone, Wuhan, Hubei Province |
| 14 | Yu Hotel | ★★★★ | 4.9 | 208 | 3.94 km | 光谷四路72号 |
| 15 | Atour Hotel Wuhan Guanggu Science and Technology Exhibition Centre Gaokeyuan | ★★★★ | 4.9 | 611 | 1.78 km | 1st Floor, BuildingC2, Changjiang Digital Cultural Center, Business Center, No.792 Gaoxin Avenue |
| 16 | JI Hotel (Wuhan Guanggu Star Hotel) | ★★★ | 4.9 | 981 | 1.37 km | Building I1, Guanggu Zhixing, No. 801 Gaoxin Avenue |
| 17 | Lavande Hotel (Wuhan Optics Valley Future Technology City) | ★★★ | 4.9 | 1713 | 3.08 km | Research Building, Yamei Biotechnology Industrial Park, No. 188 Shendun 2nd Road |
| 18 | Baiman Smart Hotel (Wuhan Guanggu Science and Technology Exhibition Centre) | ★★★ | 4.9 | 2035 | 2.14 km | 1st Floor, Building 2, Optics Valley Star City, No. 1 Shengwuyuan Road |
| 19 | Quanji Hotel (Wuhan Guanggu Huashan New City Metro Station Branch) | ★★★ | 4.9 | 128 | 5.63 km | Building D13, Phase 3, Software New City, No. 8 Huacheng Avenue, East Lake High-tech Development Zone |
| 20 | JI Hotel (Wuhan Optics Valley Gaonong Biotechnology Park) | ★★★ | 4.9 | 424 | 2.81 km | 1st-5th Floors, Building 20, Zone 1, Gaonong Biological Park, Shendun 2nd Road |