| 1 | Crowne Plaza Wuhan Optics Valley Hotel | ★★★★★ | 4.9 | 4701 | 4.78 km | No.668 Gaoxin Avenue |
| 2 | Wyndham Garden Wuhan Optics Valley Hotel | ★★★★★ | 4.9 | 4446 | 3.81 km | Building 2, No.58 Guanggu Fourth Road, Donghu New Technology Development Zone, Wuhan City |
| 3 | Wuhan Marriott Hotel Optics Valley | ★★★★★ | 4.8 | 1643 | 1.73 km | No. 797 Gaoxin Avenue |
| 4 | Moon Hotel | ★★★★ | 4.9 | 2378 | 6.67 km | No. 9 Huacheng Avenue (Wuhan Software New City) |
| 5 | Wingate by Wyndham Wuhan Optics Valley | ★★★★ | 4.9 | 2721 | 1.86 km | No.792 Gaoxin Avenue |
| 6 | Wuhan Optics Valley Technology Exhibition Center Exhibition Hotel | ★★★★ | 4.8 | 820 | 1.99 km | No.787 Gaoxin Avenue |
| 7 | Wuhan Howard Johnson Optics Valley Hotel | ★★★★ | 4.9 | 671 | 1.36 km | No.801 Gaoxin Avenue, Wuhan East Lake High-Tech Development Zone |
| 8 | Radisson Red Wuhan Optics Valley Science & Technology Exhibition Center Grand Joy City | ★★★★ | 4.9 | 2864 | 2.43 km | BuildingA1, Huaxiang Center, No. 776 Gaoxin Avenue |
| 9 | Vienna International Hotel | ★★★★ | 4.7 | 948 | 6.62 km | Hubei Natural Gas Building, 618 Guanggu Third Road, Hubei Province, China |
| 10 | IntercityHotel | ★★★★ | 4.9 | 1685 | 2.93 km | Building One, CADE Center, No. 28, Optics Valley Fifth Road, Wuhan. China |
| 11 | Hampton by Hilton Wuhan OVCEC | ★★★★ | 4.9 | 2431 | 1.34 km | No. 50 Gaokeyuan 2nd Road, East Lake High-Tech Development Zone, Wuhan, Hubei Province, China |
| 12 | Atour Hotel Wuhan Guanggu Science and Technology Exhibition Centre Gaokeyuan | ★★★★ | 4.9 | 611 | 1.78 km | 1st Floor, BuildingC2, Changjiang Digital Cultural Center, Business Center, No.792 Gaoxin Avenue |
| 13 | 丽怡酒店(武汉光谷科技会展中心大悦城店) | ★★★★ | 4.8 | 2322 | 2.65 km | Building B, Huigu Building, 768 Gaoxin Avenue |
| 14 | JI Hotel (Wuhan Guanggu Star Hotel) | ★★★ | 4.9 | 981 | 1.37 km | Building I1, Guanggu Zhixing, No. 801 Gaoxin Avenue |
| 15 | Lavande Hotel (Wuhan Optics Valley Future Technology City) | ★★★ | 4.9 | 1713 | 3.08 km | Research Building, Yamei Biotechnology Industrial Park, No. 188 Shendun 2nd Road |
| 16 | Wuhan High-tech Park Hotel (Optics Valley Technology Convention and Exhibition Center) | ★★★ | 4.8 | 487 | 1.77 km | Building B6, Gaoke Medical Device Park, No. 818 Gaoxin Avenue, East Lake High-tech Development Zone |
| 17 | JI Hotel (Wuhan Guanggu Third Road Xiaomi Science and Technology Park) | ★★★ | 4.8 | 890 | 6.64 km | No. 618 Guanggu 3rd Road |
| 18 | Lavande Hotel (Wuhan Optics Valley Technology Convention and Exhibition Center) | ★★★ | 4.8 | 1584 | 2.33 km | Building 4, Aoshan Optics Valley Century City, No. 778 Gaoxin Avenue, Donghu High-tech Development Zone |
| 19 | ECHARM Hotel (Wuhan Guanggu Biology City) | ★★★ | 4.8 | 619 | 4.08 km | No. M9, South Gate of Phase II, Mingchangli Community, Jiufeng |
| 20 | Echarm Hotel (Wuhan Optical Valley Technology Convention and Exhibition Center) | ★★★ | 4.8 | 959 | 2.21 km | Building 2, Wode Center, No. 780 Gaoxin Avenue, Donghu High-tech Development Zone |