| 1 | Crowne Plaza Wuhan Optics Valley Hotel | ★★★★★ | 4.9 | 4701 | 2.92 km | No.668 Gaoxin Avenue |
| 2 | Wyndham Garden Wuhan Optics Valley Hotel | ★★★★★ | 4.9 | 4446 | 1.78 km | Building 2, No.58 Guanggu Fourth Road, Donghu New Technology Development Zone, Wuhan City |
| 3 | Wuhan Marriott Hotel Optics Valley | ★★★★★ | 4.8 | 1643 | 0.39 km | No. 797 Gaoxin Avenue |
| 4 | Hilton Garden Inn Wuhan Optics Valley | ★★★★ | 4.8 | 475 | 3.41 km | NO.22, 39F, Block 5, Wujiao Xi’an, No. 229, Gaoxin Avenue, East Lake High-tech Development Zone, Wuhan |
| 5 | QUEENS VILLA | ★★★★ | 4.9 | 1705 | 3 km | Room Department of Erfei Villa, Optics Valley Bio-City, No. 666 Gaoxin Avenue, Donghu New Technology Development Zone, Wuhan |
| 6 | Wingate by Wyndham Wuhan Optics Valley | ★★★★ | 4.9 | 2721 | 0.51 km | No.792 Gaoxin Avenue |
| 7 | Wuhan Optics Valley Technology Exhibition Center Exhibition Hotel | ★★★★ | 4.8 | 820 | 0.39 km | No.787 Gaoxin Avenue |
| 8 | Wuhan Howard Johnson Optics Valley Hotel | ★★★★ | 4.9 | 671 | 0.98 km | No.801 Gaoxin Avenue, Wuhan East Lake High-Tech Development Zone |
| 9 | Radisson Red Wuhan Optics Valley Science & Technology Exhibition Center Grand Joy City | ★★★★ | 4.9 | 2864 | 0.41 km | BuildingA1, Huaxiang Center, No. 776 Gaoxin Avenue |
| 10 | IntercityHotel | ★★★★ | 4.9 | 1685 | 0.9 km | Building One, CADE Center, No. 28, Optics Valley Fifth Road, Wuhan. China |
| 11 | Wuhan Optics Valley 2nd Road Radisson Hotel | ★★★★ | 4.9 | 1196 | 6.32 km | No.1 Liufangyuan Cross Road |
| 12 | Wuhan Guanggu Science and Technology Exhibition Centre Qushui Lanting Resort Hotel | ★★★★ | 4.7 | 21 | 1.84 km | 光谷四路70号曲水憩园2号楼 |
| 13 | Home2 Suites by Hilton Wuhan Optics Valley | ★★★★ | 4.9 | 707 | 0.24 km | No.18, Optics Valley Avenue 6th Road, Hongshan District, Wuhan, Hubei, China |
| 14 | The Amber House Wuhan Optics Valley | ★★★★ | 4.9 | 163 | 2.45 km | Building 9, Zhiyu Future, No.17 Optics Valley 7th Road, East Lake High Technology Industrial Development |
| 15 | Golf Hotel Wuhan Yishan | ★★★★ | 4.9 | 23 | 1.14 km | 789 Gaoxin Avenue (Gaoxin Dadao) |
| 16 | JI Hotel (Wuhan Guanggu Star Hotel) | ★★★ | 4.9 | 981 | 0.91 km | Building I1, Guanggu Zhixing, No. 801 Gaoxin Avenue |
| 17 | Lavande Hotel (Wuhan Optics Valley Future Technology City) | ★★★ | 4.9 | 1713 | 3.9 km | Research Building, Yamei Biotechnology Industrial Park, No. 188 Shendun 2nd Road |
| 18 | JI Hotel (Hubei University of Economics) | ★★★ | 4.9 | 940 | 9.88 km | No.8 Yangqiaohu Avenue |
| 19 | Kyriad Marvelous Hotel Wuhan Huazhong University of Science and Technology Guanggu 1st Road | ★★★★ | 4.8 | 470 | 6.77 km | No. 6 Guanggu 1st Road |
| 20 | ECHARM Hotel (Wuhan Guanggu Biology City) | ★★★ | 4.8 | 619 | 2.62 km | No. M9, South Gate of Phase II, Mingchangli Community, Jiufeng |
