| 1 | Crowne Plaza Wuhan Optics Valley Hotel | ★★★★★ | 4.9 | 4701 | 2.92 km | No.668 Gaoxin Avenue |
| 2 | Wuhan Optics Valley Technology Exhibition Center Exhibition Hotel | ★★★★ | 4.8 | 820 | 0.39 km | No.787 Gaoxin Avenue |
| 3 | Atour Hotel (Wuhan East Railway Station Optics Valley High Tech) | ★★★★ | 4.9 | 1141 | 7.01 km | Section B, Longyue building, No.42 Guanggu 1st Road |
| 4 | Radisson Red Wuhan Optics Valley Science & Technology Exhibition Center Grand Joy City | ★★★★ | 4.9 | 2864 | 0.41 km | BuildingA1, Huaxiang Center, No. 776 Gaoxin Avenue |
| 5 | Hampton by Hilton Wuhan Guanggu First Road | ★★★★ | 4.9 | 4526 | 8.49 km | No. 16, Gaoxin 6th Road, Fozuling, East Lake High-Tech Development Zone |
| 6 | 丽怡酒店(武汉光谷科技会展中心大悦城店) | ★★★★ | 4.8 | 2322 | 0.63 km | Building B, Huigu Building, 768 Gaoxin Avenue |
| 7 | VX Hotel(Wuhan East Railway Station, Optics Valley 1st Road, Wuhan) | ★★★ | 4.7 | 1158 | 7.01 km | Building B, Longyue Building, No. 42 Guanggu 1st Rd |
| 8 | Lavande Hotel (Wuhan Optics Valley Future Technology City) | ★★★ | 4.9 | 1713 | 3.9 km | Research Building, Yamei Biotechnology Industrial Park, No. 188 Shendun 2nd Road |
| 9 | Lavande Hotel (Wuhan Optics Valley Technology Convention and Exhibition Center) | ★★★ | 4.8 | 1584 | 0.23 km | Building 4, Aoshan Optics Valley Century City, No. 778 Gaoxin Avenue, Donghu High-tech Development Zone |
| 10 | Wuxiji Boutique Hotel (Wuhan Future Science & Technology City Huawei Institute Branch) | ★★★ | 4.8 | 1155 | 2.78 km | No. 999 Gaoxin Avenue |
| 11 | ECHARM Hotel (Wuhan Guanggu Biology City) | ★★★ | 4.8 | 619 | 2.62 km | No. M9, South Gate of Phase II, Mingchangli Community, Jiufeng |
| 12 | Echarm Hotel (Wuhan Optical Valley Technology Convention and Exhibition Center) | ★★★ | 4.8 | 959 | 0.13 km | Building 2, Wode Center, No. 780 Gaoxin Avenue, Donghu High-tech Development Zone |
| 13 | Lavande Hotel (Second Guanggu Road, Wuhan) | ★★★ | 4.8 | 910 | 6.52 km | No. 6 Liufangyuan Heng Road, East Lake High-tech Development Zone |
| 14 | Metropolo wuhan Optics Valley Convention&Exhibition Center Hotel | ★★★ | 4.8 | 1335 | 0.11 km | Building 2, Wode Center, No. 780 Gaoxin Avenue, Donghu High-tech Development Zone |
| 15 | City Comfort Inn (Wuhan Guanggu 2nd Road Liufang) | ★★★ | 4.8 | 858 | 6.82 km | Building 2, Lingyun Industrial Park, No. 3 Liufangyuan Heng Road, East Lake Development Zone |
| 16 | City Preferred Hotel (Guanggu Science and Technology Exhibition Centre) | ★★★ | 4.7 | 601 | 2.52 km | 神墩五路76号多肽工业园1号研发楼1楼 |
| 17 | My Orange Hotel (Wuhan Optics Valley Technology Exhibition Center) | ★★ | 4.7 | 923 | 0.18 km | Building 7, Aoshan Century City, No. 778 Gaoxin Avenue, Guanggu 6th Road |
| 18 | Turui Hotel (Guanggu Technology Convention and Exhibition Center) | ★★ | 4.8 | 708 | 3 km | Rooms 601-610, Building 2, Wuhan National Bio E-commerce Center, No. 1 Shengwuyuan Road, East Lake High-tech Development Zone (Wuhan Area, Free Trade Zone) |
| 19 | Ruiyi Anke Hotel (Wuhan Hubei Economic College Liangshantou Community Shop) | ★★ | 4.6 | 926 | 9.18 km | 1st floor, liangshantou community, zanglong Island, China / Hubei / Wuhan / Jiangxia Economic Development Zone |
| 20 | Kerry Carl Cinema Hotel (Wuhan Optics Valley Technology Convention and Exhibition Center Branch) | ★★ | 4.5 | 509 | 0.14 km | 1st Floor, Building 2, Wode Center, No. 780 Gaoxin Avenue, Guanggu 6th Road |
